I don't believe so, and leave status will affect travel entitlements.
Double check, but I don't believe the assignments AFI permits departure from current duty station prior to DEROS month without GO level approval.
I don't recall the specifics of the leave AFI's mention of leave beginning and ending in local area, or if the AFI address leave in-conjunction with PCS.
JTR address leave status during travel status, essentially your JTR entitlements pause while leave interrupts your travel status.
The gaining MPF will want a hard date you departed last duty station (final out'd your current duty station), and will possibly throw a flag if that date is before your DEROS month, or while you are in leave status.
Finance will want to know when to charge you leave versus travel days.
I believe in order for the plan to work your current orderly room folks would have to process your leave, to include inputting a return date...then they would have to input your departed last duty station date (final out), which would have to be the day after your leave return date AND be in your DEROS month...your travel day entitlements will begin the day after your final out.
Signing in from leave and final-ing out your last duty station while you are on the road to your next duty station will probably raise some eyebrows.
My knowledge on all this is dated but I researched it all when I left my assignment in Canada eight years ago.