If I throw an acronym out there that isn't common knowledge, I almost always provide a translation. I also take the time to learn what acronyms are before using them:
How many of you know what these acronyms stand for (not just what they are) without looking them up:
Medical:MRI
Military:CALCM
Biology:DNA
Football:PAT
Military:AWACS
Military:ALICE
Military:LNO
Military:HMMWV
Military:MOLLE
Military:MOPP
Military:SCIF
Military:JDAM
You'll probably get a few.
Short version, we're all guilty of it. Just spell them out if they aren't 100% clear.